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DeCS
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Descriptor English:
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ATP-Binding Cassette, Sub-Family B, Member 1
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Descriptor Spanish:
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Miembro 1 de la Subfamilia B de Casetes de Unión a ATP
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Descriptor Portuguese:
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Membro 1 da Subfamília B de Cassetes de Ligação de ATP
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Synonyms English:
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ABCB1 Protein
CD243 Antigen
PGY-1 Protein
Antigen, CD243
P Glycoprotein
PGY 1 Protein
MDR1 Protein
Multidrug Resistance Protein 1
P-Glycoprotein
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Tree Number:
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D12.776.157.530.100.652.500
D12.776.157.530.450.074.500.500.875.500
D12.776.395.550.020.610.610
D12.776.543.550.192.610.610
D12.776.543.585.100.610.500
D12.776.543.585.450.074.500.500.875.500
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Definition English:
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A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). |
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Indexing Annotation English:
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note entry term: ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B is also available
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Entry Combination - descr/qualif English:
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ATP-Binding Cassette, Sub-Family B, Member 1/analogs & derivatives use ATP Binding Cassette Transporter, Sub-Family B
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See Related English:
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Drug Resistance, Multiple
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History Note English:
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2018 (1995)
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Allowable Qualifiers English:
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Record Number:
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32100
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Unique Identifier:
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D020168
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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